Description

(3-Chloro-4-Iodopyridin-2-Yl)Amine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional halogen pattern (chloro and iodo) makes it an indispensable intermediate for constructing complex molecular architectures, particularly in pharmaceutical discovery. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small molecule drugs, especially kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Research: Used to develop novel pesticides and herbicides by acting as a core scaffold for bioactive molecules.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Functional Material Development: A building block for organic electronic materials, such as those used in OLEDs or conductive polymers.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	(3-Chloro-4-Iodopyridin-2-Yl)Amine
CAS No.	1152617-24-7
Molecular Formula	C5H4ClIN2
Molecular Weight	254.46 g/mol
Synonyms	2-Amino-3-chloro-4-iodopyridine; 3-Chloro-4-iodopyridin-2-amine; 4-Iodo-3-chloropyridin-2-amine; 3-Chloro-4-iodo-2-pyridinamine; (3-Chloro-4-iodo-2-pyridinyl)amine; 2-Pyridinamine, 3-chloro-4-iodo-; 1152617-24-7 (CAS); 3-Chloro-4-iodo-2-aminopyridine
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be kept in the original packaging or an amber vial until use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.