Description

4-(1H-Pyrazol-1-Yl)Pyridine-2-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique pyridine-pyrazole core structure makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand in Catalysis: Serves as a precursor for creating specialized ligands used in transition metal-catalyzed reactions.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its chelating potential.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and tools to study biological processes.

Basic Information

Product Name	4-(1H-Pyrazol-1-Yl)Pyridine-2-Carboxylic Acid
CAS No.	1152523-86-8
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	4-(1H-Pyrazol-1-yl)pyridine-2-carboxylic acid; 4-(Pyrazol-1-yl)picolinic acid; 2-Pyridinecarboxylic acid, 4-(1H-pyrazol-1-yl)-; 4-(1H-Pyrazol-1-yl)-2-pyridinecarboxylic acid; 1152523-86-8; 4-Pyrazol-1-yl-pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(1H-Pyrazol-1-Yl)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be kept away from incompatible materials. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.