Description

tert-Butyl 2-Nitropyridin-4-Ylcarbamate is a specialized chemical intermediate featuring a nitro-substituted pyridine core protected by a tert-butyl carbamate group. This compound is valued for its role as a versatile building block in the synthesis of more complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized pyridine or aminopyridine motifs.
• Agrochemical Synthesis: Used in research for developing new herbicides, fungicides, or insecticides where the nitro and protected amine groups offer sites for further chemical modification.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands used in catalytic systems.
• Material Science Research: Employed in the development of organic electronic materials or functional polymers due to its electron-deficient aromatic system.
• Chemical Biology Probes: Useful for synthesizing tagged or modified molecules used to study biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	tert-Butyl 2-Nitropyridin-4-Ylcarbamate
CAS No.	1152428-55-1
Molecular Formula	C10H13N3O4
Molecular Weight	239.23 g/mol
Synonyms	tert-Butyl N-(2-nitropyridin-4-yl)carbamate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-nitropyridine; 2-Nitro-4-[(tert-butoxycarbonyl)amino]pyridine; 4-(Boc-amino)-2-nitropyridine; Boc-4-amino-2-nitropyridine; tert-Butyl (2-nitropyridin-4-yl)carbamate; 4-Amino-2-nitropyridine tert-butyl carbamate; 2-Nitro-4-pyridinylcarbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Nitropyridin-4-Ylcarbamate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.