Description

tert-Butyl 1-(Pyridin-4-Ylmethyl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with a pyridinylmethyl substituent and a Boc-protected amine. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve pharmacokinetic properties.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and receptor interactions in biological systems.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Library Synthesis: Used to generate diverse compound libraries for high-throughput screening (HTS) in drug discovery programs.

Basic Information

Product Name	tert-Butyl 1-(Pyridin-4-Ylmethyl)Piperidin-4-Ylcarbamate
CAS No.	1152424-96-8
Molecular Formula	C17H27N3O2
Molecular Weight	305.42 g/mol
Synonyms	1-Boc-4-(Aminomethyl)-1-(4-Pyridylmethyl)piperidine; tert-Butyl N-[1-[(Pyridin-4-yl)methyl]piperidin-4-yl]carbamate; 1-(4-Pyridylmethyl)-4-(Boc-amino)piperidine; 4-[[(tert-Butoxycarbonyl)amino]-1-(4-pyridinylmethyl)piperidine; 1-(Pyridin-4-ylmethyl)piperidin-4-amine, N-Boc protected; BOC-4-Amino-1-(4-Pyridylmethyl)piperidine; 1152424-96-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(Pyridin-4-Ylmethyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.