Description

3-(Trifluoromethyl)-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine is a high-value fluorinated heterocyclic building block, essential for advanced organic synthesis. Its unique pyrrolopyridine scaffold, functionalized with a trifluoromethyl group, makes it a critical intermediate for modulating the physicochemical properties of target molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a building block for functional organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize potency, selectivity, and metabolic stability of lead compounds.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex fluorinated heterocycles.

Basic Information

Product Name	3-(Trifluoromethyl)-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1150618-34-0
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	2,3-Dihydro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 3-(Trifluoromethyl)-1H,2H,3H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro-3-(trifluoromethyl)-; 1150618-34-0; 3-Trifluoromethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 3-(Trifluoromethyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 3-(Trifluoromethyl)-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for advanced intermediates, ensuring reliability for critical pharmaceutical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.