Description

2-Chloro-5,6-Dihydrocyclopenta[B]Pyridin-7-One is a high-purity, advanced pharmaceutical intermediate characterized by its fused cyclopentapyridinone core structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drugs.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the multi-step synthesis of complex target molecules for preclinical and clinical evaluation.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing complex heterocyclic systems.

Basic Information

Product Name	2-Chloro-5,6-Dihydrocyclopenta[B]Pyridin-7-One
CAS No.	1150617-92-7
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	2-Chloro-5,6-dihydrocyclopenta[b]pyridin-7(1H)-one; 2-Chloro-5,6-dihydro-1H-cyclopenta[b]pyridin-7-one; 7(1H)-Cyclopenta[b]pyridinone, 2-chloro-5,6-dihydro-; 2-Chlorocyclopentapyridinone; CAS 1150617-92-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6-Dihydrocyclopenta[B]Pyridin-7-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and non-GMP pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.