Description

3-Methoxy-2-(Pyrrolidin-2-Yl)Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1150617-89-2. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for building complex molecules with targeted biological activity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up and commercial production of APIs.
• Bioconjugation & Prodrug Synthesis: Utilized in the design of prodrugs or bioconjugates to improve drug delivery and pharmacokinetics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	3-Methoxy-2-(Pyrrolidin-2-Yl)Pyridine Hydrochloride
CAS No.	1150617-89-2
Molecular Formula	C10H15ClN2O
Molecular Weight	214.69 g/mol
Synonyms	2-(2-Pyrrolidinyl)-3-methoxypyridine hydrochloride; 3-Methoxy-2-(2-pyrrolidinyl)pyridine HCl; 3-Methoxy-2-pyrrolidin-2-ylpyridine hydrochloride; 2-(3-Methoxypyridin-2-yl)pyrrolidine hydrochloride; Pyrrolidine, 2-(3-methoxy-2-pyridinyl)-, hydrochloride (1:1); 1150617-89-2; UNII-8G7J9J4K6H
EINECS	Contact for details

Quality Control

Our 3-Methoxy-2-(Pyrrolidin-2-Yl)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.