Description

7-Chloro-1-(propan-2-yl)-1H-pyrrolo[2,3-c]pyridine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyridine class of heterocyclic compounds. This specialized building block is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking a reliable and high-quality source for complex molecular synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel small-molecule drug candidates.
• Kinase Inhibitor Research: Used in the synthesis of compounds targeting specific kinase enzymes relevant in cancer and inflammatory diseases.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biological target identification and validation.

Basic Information

Product Name	7-Chloro-1-(propan-2-yl)-1H-pyrrolo[2,3-c]pyridine
CAS No.	1150617-64-3
Molecular Formula	C10H11ClN2
Molecular Weight	194.66 g/mol
Synonyms	7-Chloro-1-isopropyl-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine, 7-chloro-1-(1-methylethyl)-; 7-Chloro-1-(1-methylethyl)-1H-pyrrolo[2,3-c]pyridine; 7-Chloro-1-isopropyl-pyrrolo[2,3-c]pyridine; 1150617-64-3; 7-Chloro-1-(propan-2-yl)-1H-pyrrolo[2,3-c]pyridine; 1-Isopropyl-7-chloro-1H-pyrrolo[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Our 7-Chloro-1-(propan-2-yl)-1H-pyrrolo[2,3-c]pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.