Description

6-Bromo-1H-Pyrazolo[4,3-B]Pyridine is a high-value brominated heterocyclic compound serving as a critical building block in advanced organic synthesis. Its fused pyrazolopyridine core, functionalized with a reactive bromine atom, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it is used to introduce the pyrazolopyridine pharmacophore.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require the pyrazolopyridine scaffold.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Proteomics: Employed as a tagging or linking agent in the design of molecular probes and bioconjugates.
• Academic & Contract Research: Utilized in methodological studies and as a standard in heterocyclic chemistry research within university and CRO laboratories.

Basic Information

Product Name	6-Bromo-1H-Pyrazolo[4,3-B]Pyridine
CAS No.	1150617-54-1
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	6-Bromo-1H-pyrazolo[4,3-b]pyridine; 6-Bromo-1H-pyrazolo[4,3-b]pyridin; 6-Bromopyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine, 6-bromo-; 1150617-54-1; 6-Bromo-1H-pyrazolo[4,3-b]pyridine (9CI); 6-Bromo-1H-pyrazolo[4,3-b]pyridine, 6-Bromo-1H-pyrazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-1H-Pyrazolo[4,3-B]Pyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.