Description

2-(N’-Acetylhydrazino)-5-Chloro-3-Fluoropyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring both chloro and fluoro substituents on the pyridine ring, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors who require reliable, high-quality intermediates for lead optimization and process development.

Application

This specialized pyridine derivative serves as a versatile synthon in various research and industrial applications:

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Potential precursor for the development of specialty chemicals and functional materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process scale-up services.

Basic Information

Product Name	2-(N’-Acetylhydrazino)-5-Chloro-3-Fluoropyridine
CAS No.	1150561-82-2
Molecular Formula	C7H7ClFN3O
Molecular Weight	203.60 g/mol
Synonyms	5-Chloro-3-fluoro-2-(2-acetylhydrazinyl)pyridine; 2-(2-Acetylhydrazinyl)-5-chloro-3-fluoropyridine; 2-Acetylhydrazino-5-chloro-3-fluoropyridine; 5-Chloro-3-fluoro-2-(N-acetylhydrazino)pyridine; 2-Hydrazinyl-5-chloro-3-fluoropyridine, N-acetyl derivative; 1150561-82-2; 2-(N-Acetylhydrazino)-5-chloro-3-fluoropyridine
EINECS	Contact for details

Quality Control

Our production of 2-(N’-Acetylhydrazino)-5-Chloro-3-Fluoropyridine adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical research and development processes. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting regulatory submissions and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.