Description

2-Bromo-4-Hydroxynicotinic Acid is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated hydroxynicotinic acid structure makes it a valuable intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent synthesis.
• Agrochemical Research: Used as a precursor in the creation of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a functionalized starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science: Building block for the synthesis of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Item	Details
Product Name	2-Bromo-4-Hydroxynicotinic Acid
CAS No.	1150561-81-1
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	4-Hydroxy-2-bromonicotinic acid; 2-Bromo-4-hydroxypyridine-3-carboxylic acid; 3-Carboxy-2-bromo-4-hydroxypyridine; 2-Bromo-4-pyridinol-3-carboxylic acid; Nicotinic acid, 2-bromo-4-hydroxy-; 1150561-81-1; 2-Bromo-4-hydroxy-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Hydroxynicotinic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.