Description

2-Bromo-6-(Pyrrolidin-1-Yl)Pyridine-4-Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining a halogenated pyridine core with a pyrrolidine substituent and a boronic acid functional group, makes it an indispensable reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds, which are core structures in many drug candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Used to create novel heterocyclic compounds for the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and charge-transport materials, due to its electron-donating pyrrolidine group and planar pyridine-boronic acid motif.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes and sensors used in diagnostic assays and cellular imaging.
• Catalyst & Ligand Synthesis: Utilized to construct sophisticated nitrogen-containing ligands for transition metal catalysis, enhancing reaction selectivity and yield in fine chemical production.

Basic Information

Product Name	2-Bromo-6-(Pyrrolidin-1-Yl)Pyridine-4-Boronic Acid
CAS No.	1150271-64-9
Molecular Formula	C9H12BBrN2O2
Molecular Weight	271.92 g/mol
Synonyms	2-Bromo-6-(1-pyrrolidinyl)-4-pyridineboronic acid; 4-Borono-2-bromo-6-(pyrrolidin-1-yl)pyridine; 2-Bromo-6-pyrrolidin-1-ylpyridine-4-boronic acid; (2-Bromo-6-(pyrrolidin-1-yl)pyridin-4-yl)boronic acid; 1150271-64-9; BRN 19117536
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-(Pyrrolidin-1-Yl)Pyridine-4-Boronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and allowed to equilibrate to room temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.