Description

Ethyl1-(5-Chloro-3-Fluoropyridin-2-Yl)-5-Methylpyrazole-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1150164-40-1. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the agrochemical and pharmaceutical research sectors. It is primarily sought by R&D chemists and process development scientists working on the next generation of crop protection agents and targeted therapeutics.

Application

This specialized pyrazole-carboxylate derivative serves as a key building block in sophisticated organic synthesis. Its primary and related applications include:

• Agrochemical Intermediate: A crucial precursor in the synthesis of modern insecticides and fungicides, targeting specific pest enzymes.
• Pharmaceutical Research: Used in medicinal chemistry for constructing heterocyclic cores in drug discovery programs, particularly for kinase inhibitors.
• Chemical Synthesis: Acts as a versatile synthon for introducing the 5-chloro-3-fluoropyridin-2-yl moiety into more complex molecular architectures.
• Process Development: Serves as a standard reference material for scaling up production processes in fine chemical manufacturing.

Basic Information

Product Name	Ethyl1-(5-Chloro-3-Fluoropyridin-2-Yl)-5-Methylpyrazole-4-Carboxylate
CAS No.	1150164-40-1
Molecular Formula	C12H11ClFN3O2
Molecular Weight	283.69 g/mol
Synonyms	Ethyl 1-(5-Chloro-3-fluoropyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylate; 1-(5-Chloro-3-fluoro-2-pyridinyl)-5-methyl-1H-pyrazole-4-carboxylic acid ethyl ester; 5-Chloro-3-fluoro-2-(5-methyl-4-(ethoxycarbonyl)-1H-pyrazol-1-yl)pyridine; Ethyl 5-methyl-1-(5-chloro-3-fluoro-2-pyridyl)pyrazole-4-carboxylate; 1150164-40-1; CAS 1150164-40-1
EINECS	Contact for details

Quality Control

Our production of Ethyl1-(5-Chloro-3-Fluoropyridin-2-Yl)-5-Methylpyrazole-4-Carboxylate adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.