Description

6-Butoxy-5-Chloropyridine-3-Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile building block for constructing complex molecules via cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides, leveraging the pyridine core for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized organic materials, including ligands for catalysts and monomers for specialty polymers.
• Suzuki-Miyaura Cross-Coupling: The quintessential application, enabling the formation of carbon-carbon bonds between the boronic acid group and various organic halides under palladium catalysis.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological evaluation.
• Ligand and Catalyst Design: The pyridine-boronic acid structure makes it useful for developing novel chelating ligands and organocatalysts.

Basic Information

Product Name	6-Butoxy-5-Chloropyridine-3-Boronic Acid
CAS No.	1150114-71-8
Molecular Formula	C9H13BClNO3
Molecular Weight	229.47 g/mol
Synonyms	(6-Butoxy-5-chloropyridin-3-yl)boronic acid; 5-Chloro-6-butoxypyridine-3-boronic acid; 3-Borono-5-chloro-6-butoxypyridine; Boronic acid, B-(5-chloro-6-butoxy-3-pyridinyl)-; 5-Chloro-6-n-butoxy-3-pyridineboronic acid; 1150114-71-8; 6-n-Butoxy-5-chloropyridine-3-boronic acid
EINECS	Contact for details

Quality Control

Our 6-Butoxy-5-Chloropyridine-3-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP standards where applicable, and our quality systems are designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.