Description

3-Chloro-2-Fluoropyridine-4-Carboxaldehyde is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluoropyridine scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its reactive aldehyde and halogen groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	3-Chloro-2-Fluoropyridine-4-Carboxaldehyde
CAS No.	1149587-02-9
Molecular Formula	C6H3ClFNO
Molecular Weight	159.54 g/mol
Synonyms	2-Fluoro-3-chloropyridine-4-carboxaldehyde; 4-Formyl-3-chloro-2-fluoropyridine; 3-Chloro-2-fluoroisonicotinaldehyde; 3-Chloro-2-fluoro-4-pyridinecarboxaldehyde; 2-Fluoro-3-chloroisonicotinaldehyde; 1149587-02-9; 3-Chloro-2-fluoropyridine-4-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Fluoropyridine-4-Carboxaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.