Description

Methyl 3-Bromo-4-Carbamoylbenzoate CAS NO 1149388-50-0 is a high-purity, multi-functional organic building block characterized by its bromine and carboxamide functional groups. This compound is essential for advanced organic synthesis, enabling the precise construction of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting specific receptor sites where the bromine atom facilitates further functionalization.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging its benzoate core for bioactive molecule design.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings.
• Material Science Precursor: Employed in the research and development of advanced organic materials, including polymers and liquid crystals with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 3-Bromo-4-Carbamoylbenzoate
CAS No.	1149388-50-0
Molecular Formula	C9H8BrNO3
Molecular Weight	258.07 g/mol
Synonyms	Methyl 3-bromo-4-carbamoylbenzoate; 3-Bromo-4-(aminocarbonyl)benzoic acid methyl ester; Methyl 3-bromo-4-(aminocarbonyl)benzoate; Benzoic acid, 3-bromo-4-(aminocarbonyl)-, methyl ester; 4-Carbamoyl-3-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-4-Carbamoylbenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.