Description

1-tert-Butyl 2-Methyl 2-(3-Methylbut-2-Enyl)Azetidine-1,2-Dicarboxylate is a high-purity, protected azetidine derivative serving as a critical chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those containing the azetidine ring system.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis.
• Peptidomimetics: Employed in the construction of conformationally constrained peptide analogs for medicinal chemistry programs.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and new reaction development.
• Fine Chemical Production: Used in the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	1-tert-Butyl 2-Methyl 2-(3-Methylbut-2-Enyl)Azetidine-1,2-Dicarboxylate
CAS No.	1148044-26-1
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	2-(3-Methylbut-2-en-1-yl)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)azetidine; 1-Boc-2-(methoxycarbonyl)-2-(3-methylbut-2-en-1-yl)azetidine; 2-(3-Methyl-2-butenyl)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)azetidine; tert-Butyl 2-(methoxycarbonyl)-2-(3-methylbut-2-en-1-yl)azetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-(methoxycarbonyl)-2-(3-methyl-2-butenyl)azetidine; Azetidine-1,2-dicarboxylic acid, 2-(3-methyl-2-butenyl)-, 1-(1,1-dimethylethyl) 2-methyl ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 2-Methyl 2-(3-Methylbut-2-Enyl)Azetidine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and chiral integrity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.