Description

5-Chloro-6-Phenylpyridine-3-Carboxylic Acid is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with precise halogen and carboxylic acid functionality. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or molecular components for OLEDs.
• Custom Chemical Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	5-Chloro-6-Phenylpyridine-3-Carboxylic Acid
CAS No.	1148027-23-9
Molecular Formula	C12H8ClNO2
Molecular Weight	233.65 g/mol
Synonyms	5-Chloro-6-phenylnicotinic acid; 3-Pyridinecarboxylic acid, 5-chloro-6-phenyl-; 5-Chloro-6-phenyl-3-pyridinecarboxylic acid; 6-Phenyl-5-chloropyridine-3-carboxylic acid; 5-Chloro-6-phenyl-pyridine-3-carboxylic acid; 1148027-23-9 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Phenylpyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with client specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.