Description

Benzyl 4-(Trimethylsilyloxy)-5,6-dihydropyridine-1(2H)-carboxylate CAS NO 1147998-34-2 is a high-value, organosilicon-protected intermediate crucial for advanced synthetic chemistry. This compound is specifically engineered to provide a stable, reactive handle for the controlled synthesis of complex nitrogen-containing heterocycles, which are foundational scaffolds in modern pharmaceuticals. It is an essential building block for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients with improved efficacy.

Application

• Pharmaceutical Intermediate: A key protected synthon for the synthesis of piperidine and related alkaloid derivatives used in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Research: Serves as a precursor for novel nitrogen-containing heterocycles with potential insecticidal or herbicidal activity.
• Fine Chemical Synthesis: Used in the multi-step preparation of complex natural products, ligands for catalysis, and specialty materials.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, particularly those involving silyl protecting group strategies.

Basic Information

Product Name	Benzyl 4-(Trimethylsilyloxy)-5,6-dihydropyridine-1(2H)-carboxylate
CAS No.	1147998-34-2
Molecular Formula	C16H23NO3Si
Molecular Weight	305.45 g/mol
Synonyms	Benzyl 4-(trimethylsilyloxy)-1,2,3,6-tetrahydropyridine-1-carboxylate; 1-(Benzyloxycarbonyl)-4-[(trimethylsilyl)oxy]-1,2,3,6-tetrahydropyridine; 4-(Trimethylsilyloxy)-1,2,3,6-tetrahydropyridine-1-carboxylic Acid Benzyl Ester; 1-CBz-4-OTMS-1,2,3,6-tetrahydropyridine; 4-TMS-Oxy-Cbz-tetrahydropyridine; Benzyl N-Carboxy-4-(trimethylsilyloxy)-2,3-dihydropyridine; 1,2,3,6-Tetrahydro-4-[(trimethylsilyl)oxy]-1-pyridinecarboxylic Acid Phenylmethyl Ester
EINECS	Contact for details

Quality Control

Every batch of Benzyl 4-(Trimethylsilyloxy)-5,6-dihydropyridine-1(2H)-carboxylate is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.