Description

1H-Pyrrolo[2,3-B]Pyridine, 1-(Phenylsulfonyl)-5-(1H-Pyrazol-4-Yl)- is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This heterocyclic compound is specifically engineered for use in the synthesis of targeted therapeutic agents, offering a critical building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers focused on developing novel kinase inhibitors and other small-molecule drugs.

Application

This specialized intermediate serves as a key scaffold in several high-value research and development applications:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel kinase inhibitors targeting various oncology and inflammatory pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new drug candidates.
• Biochemical Tool Compound Development: Serves as a precursor for creating probes and inhibitors used in biological target validation and assay development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client drug discovery programs.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 1-(Phenylsulfonyl)-5-(1H-Pyrazol-4-Yl)-
CAS No.	1147998-27-3
Molecular Formula	C16H12N4O2S
Molecular Weight	324.36 g/mol
Synonyms	1-(Phenylsulfonyl)-5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine; 5-(1H-Pyrazol-4-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-5-(1H-pyrazol-4-yl)-; 1-Benzenesulfonyl-5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine; 1147998-27-3; 1-(Phenylsulfonyl)-5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine, 1-(Phenylsulfonyl)-5-(1H-Pyrazol-4-Yl)- adheres to stringent quality protocols suitable for pharmaceutical R&D applications. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.