Description

Methyl 3-Chloro-2-Methoxy-5-(Trifluoromethyl)Isonicotinate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular architecture, featuring a chlorinated, methoxylated, and trifluoromethylated pyridine core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a crucial building block for the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and chloro substituents.
• Material Science Research: Used in the synthesis of advanced organic materials, such as liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs), where its structural motifs can influence electronic and self-assembly properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	Methyl 3-Chloro-2-Methoxy-5-(Trifluoromethyl)Isonicotinate
CAS No.	1147979-36-9
Molecular Formula	C9H7ClF3NO3
Molecular Weight	269.60 g/mol
Synonyms	Methyl 3-chloro-2-methoxy-5-(trifluoromethyl)pyridine-4-carboxylate; 3-Chloro-2-methoxy-5-(trifluoromethyl)isonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 3-chloro-2-methoxy-5-(trifluoromethyl)-, methyl ester; Methyl 3-chloro-2-methoxy-5-trifluoromethylisonicotinate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Chloro-2-Methoxy-5-(Trifluoromethyl)Isonicotinate adheres to stringent in-process and final release controls to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed and stored in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.