Description

6-(Benzyloxy)-2-Azaspiro[3.3]Heptane is a high-value, spirocyclic amine derivative featuring a benzyl-protected oxygen functionality. This compound serves as a versatile and critical pharmaceutical intermediate and building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its constrained spirocyclic scaffold.
• Agrochemical Synthesis: Intermediate for developing new generation herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or additive for creating specialty polymers with unique thermal or mechanical properties.

Basic Information

Product Name	6-(Benzyloxy)-2-Azaspiro[3.3]Heptane
CAS No.	1147557-98-9
Molecular Formula	C14H19NO
Molecular Weight	217.31 g/mol
Synonyms	2-Azaspiro[3.3]heptan-6-ol, benzyl ether; 6-(Phenylmethoxy)-2-azaspiro[3.3]heptane; 2-Azaspiro[3.3]heptane, 6-(benzyloxy)-; Benzyl 2-azaspiro[3.3]heptan-6-yl ether; 6-O-Benzyl-2-azaspiro[3.3]heptane; 2-Aza-6-(benzyloxy)spiro[3.3]heptane; BnO-2-Azaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our 6-(Benzyloxy)-2-Azaspiro[3.3]Heptane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.