Description

Octahydro-Pyrrolo[3,2-C]Pyridine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex, saturated bicyclic nitrogen heterocycle. This compound is critical for medicinal chemistry research and development, serving as a key building block for constructing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the synthesis of complex molecules targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry.
• API Synthesis: Used in the research and development of Active Pharmaceutical Ingredients (APIs) with complex polycyclic structures.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of compounds for biological screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: The pyrrolopyridine core structure is of significant interest for developing therapeutics for neurological and psychiatric conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Used in university and institutional labs for advanced synthetic organic chemistry and pharmacology projects.

Basic Information

Product Name	Octahydro-Pyrrolo[3,2-C]Pyridine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1147422-00-1
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	1-Boc-octahydropyrrolo[3,2-c]pyridine; tert-Butyl octahydropyrrolo[3,2-c]pyridine-1-carboxylate; 1-(tert-Butoxycarbonyl)octahydropyrrolo[3,2-c]pyridine; Octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid, 1,1-dimethylethyl ester; BOC-Octahydropyrrolo[3,2-c]pyridine; 1-N-Boc-octahydropyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our Octahydro-Pyrrolo[3,2-C]Pyridine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material suitable for advanced research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.