Description

(2S)-Methyl 2-(2-Chlorophenyl)-2-(2-Oxo-7,7A-Dihydrothieno[3,2-C]Pyridin-5(2H,4H,6H)-Yl)Acetate is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound, with CAS number 1147350-75-1, is valued for its complex heterocyclic structure which serves as a key building block in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel thienopyridine-based molecular frameworks.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate in scaling up API manufacturing processes under GMP conditions.
• Asymmetric Synthesis: Utilized in studies and applications requiring high enantiomeric purity due to its defined (2S) stereochemistry.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(2S)-Methyl 2-(2-Chlorophenyl)-2-(2-Oxo-7,7A-Dihydrothieno[3,2-C]Pyridin-5(2H,4H,6H)-Yl)Acetate
CAS No.	1147350-75-1
Molecular Formula	C17H16ClNO3S
Molecular Weight	349.83 g/mol
Synonyms	Methyl (2S)-2-(2-chlorophenyl)-2-(2-oxo-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5(2H)-yl)acetate; (2S)-Methyl 2-(2-Chlorophenyl)-2-(2-Oxo-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5(2H)-yl)acetate; 1147350-75-1; UNII-9Q4Q2I8F0F; 9Q4Q2I8F0F; SCHEMBL23346877; DTXSID60674488; AKOS040759232.
EINECS	Contact for details

Quality Control

Our (2S)-Methyl 2-(2-Chlorophenyl)-2-(2-Oxo-7,7A-Dihydrothieno[3,2-C]Pyridin-5(2H,4H,6H)-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under inert atmosphere when handling is required for prolonged periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.