Description

5-Chloro-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine is a high-value heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its fused pyrrolopyridine core.
• Material Science Research: Serves as a precursor for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	5-Chloro-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1146970-26-4
Molecular Formula	C7H7ClN2
Molecular Weight	154.60 g/mol
Synonyms	5-Chloro-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1,2,3,4-tetrahydropyrrolo[2,3-b]pyridine; 5-Chloro-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 1146970-26-4; Pyrrolo[2,3-b]pyridine, 5-chloro-2,3-dihydro-; 5-Chloro-1H,2H,3H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.