Description

D-Serine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Ethyl Ester is a protected amino acid derivative, specifically a Boc-protected serine ethyl ester, which serves as a crucial chiral building block in organic synthesis. This compound is essential for the controlled introduction of the serine moiety into peptide chains and complex molecules, offering enhanced stability and selectivity during multi-step reactions. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide-based drugs, and advanced biochemical probes.

Application

• Peptide Synthesis: A key intermediate in solid-phase and solution-phase peptide synthesis for constructing serine-containing sequences.
• Pharmaceutical Intermediates: Serves as a vital chiral synthon in the research and production of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation & Linker Chemistry: Used in the preparation of modified peptides and protein conjugates for drug delivery systems and diagnostic agents.
• Chemical Biology Research: Employed in the synthesis of enzyme inhibitors, receptor ligands, and other bioactive molecules for mechanistic studies.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in stereoselective chemical transformations.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) protecting group allows for orthogonal deprotection in complex multi-functional molecule assembly.

Basic Information

Product Name	D-Serine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Ethyl Ester
CAS No.	1146954-88-2
Molecular Formula	C10H19NO5
Molecular Weight	233.26 g/mol
Synonyms	Boc-D-serine ethyl ester; (R)-2-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoic acid ethyl ester; Ethyl (R)-2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate; D-Ser-OEt·HCl Boc; N-Boc-D-serine ethyl ester; Boc-D-Ser-OEt; N-(tert-Butoxycarbonyl)-D-serine ethyl ester
EINECS	Contact for details

Quality Control

Our D-Serine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.