Description

3-Bromo-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a bromo-substituent for cross-coupling reactions with a trifluoromethyl group that imparts desirable physicochemical properties to target molecules. It is primarily needed by pharmaceutical, agrochemical, and material science R&D teams for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging the bioactivity of the imidazopyridine core.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient character.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Fluorine Chemistry: The trifluoromethyl group is utilized to modulate lipophilicity, metabolic stability, and binding affinity in lead optimization.
• Chemical Biology Probes: Used in the synthesis of labeled compounds and molecular probes for target identification and validation studies.

Basic Information

Product Name	3-Bromo-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine
CAS No.	1146615-86-2
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	3-Bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 3-bromo-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-3-bromoimidazo[1,2-a]pyridine; 3-Bromo-6-trifluoromethylimidazo[1,2-a]pyridine; 1146615-86-2; 3-Bromo-6-(trifluoromethyl)-imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.