Description

1-[1-(4-Amino-2-Pyridinyl)-4-Phenyl-4-Piperidinyl]Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Neurological & CNS Drug Development: Serves as a core scaffold for developing potential therapeutics for neurological disorders, given its piperidine-pyridine pharmacophore.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic & Institutional Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacological studies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	1-[1-(4-Amino-2-Pyridinyl)-4-Phenyl-4-Piperidinyl]Ethanone
CAS No.	1146514-70-6
Molecular Formula	C18H21N3O
Molecular Weight	295.38 g/mol
Synonyms	1-[1-(4-Amino-2-pyridinyl)-4-phenyl-4-piperidinyl]ethanone; 1-(1-(4-Amino-2-pyridyl)-4-phenyl-4-piperidyl)ethanone; 1-(1-(4-Aminopyridin-2-yl)-4-phenylpiperidin-4-yl)ethanone; 4-Phenyl-1-(4-amino-2-pyridinyl)-4-piperidinyl methyl ketone; 1146514-70-6; Ethanone, 1-[1-(4-amino-2-pyridinyl)-4-phenyl-4-piperidinyl]-; CAS 1146514-70-6
EINECS	Contact for details

Quality Control

Our 1-[1-(4-Amino-2-Pyridinyl)-4-Phenyl-4-Piperidinyl]Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), identity confirmation, and impurity profiles is provided with every shipment to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.