Description

5-Bromo-2-Chloropyridine-3-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate essential for advanced synthesis. Its unique halogenated pyridine-sulfonyl chloride structure makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogen and sulfonyl chloride reactivity.
• Material Science Research: Serves as a building block for creating functional polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes and affinity labels.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-2-Chloropyridine-3-Sulfonyl Chloride
CAS No.	1146290-19-8
Molecular Formula	C5H2BrCl2NO2S
Molecular Weight	315.95 g/mol
Synonyms	3-Chlorosulfonyl-5-bromo-2-chloropyridine; 2-Chloro-5-bromopyridine-3-sulfonyl chloride; 5-Bromo-2-chloro-3-pyridinesulfonyl chloride; 1146290-19-8; 5-Br-2-Cl-Py-3-SO2Cl
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloropyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports your regulatory needs in cGMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.