Description

tert-Butyl 3-(6-Bromopyridin-3-yl)oxyazetidine-1-carboxylate is a high-value, protected azetidine building block featuring a bromopyridine moiety, designed for advanced organic synthesis. This compound is critical for medicinal chemistry research and pharmaceutical development, enabling the rapid construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry: Used in parallel and combinatorial library synthesis for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Research: Serves as a versatile precursor in the synthesis of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: The bromopyridine group is a useful handle for creating novel ligands for transition metal catalysis.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological target identification and validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 3-(6-Bromopyridin-3-yl)oxyazetidine-1-carboxylate
CAS No.	1146089-80-6
Molecular Formula	C13H17BrN2O3
Molecular Weight	329.19 g/mol
Synonyms	1-Boc-3-((6-bromopyridin-3-yl)oxy)azetidine; 3-[(6-Bromo-3-pyridinyl)oxy]-1-[(1,1-dimethylethoxy)carbonyl]azetidine; tert-Butyl 3-((6-bromopyridin-3-yl)oxy)azetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-((6-bromopyridin-3-yl)oxy)azetidine; Azetidine, 3-[(6-bromo-3-pyridinyl)oxy]-1-[(1,1-dimethylethoxy)carbonyl]-; Boc-Azetidine-3-yloxy-6-bromopyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(6-Bromopyridin-3-yl)oxyazetidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO 9001 compliant workflows for our global pharmaceutical and research clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.