Description

Methyl 6-Phenyl-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in pharmaceutical discovery, offering a versatile scaffold for creating novel active ingredients. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new products with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used as a building block for developing new generation pesticides and herbicides with improved efficacy and selectivity.
• Material Science: Acts as a monomer or functional additive in the development of specialty polymers and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for target validation and mechanistic studies.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex molecules.
• Academic & Contract Research: Essential for exploratory synthetic chemistry in university labs and CROs (Contract Research Organizations).

Basic Information

Product Name	Methyl 6-Phenyl-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate
CAS No.	1146081-24-4
Molecular Formula	C16H11F3N2O2
Molecular Weight	320.27 g/mol
Synonyms	Methyl 6-Phenyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 6-phenyl-4-(trifluoromethyl)-, methyl ester; 6-Phenyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; Methyl 6-phenyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; CAS 1146081-24-4
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Phenyl-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality systems support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.