Description

3-[2-(Morpholine-4-Carbonyl)-Phenoxy]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) advanced pharmaceutical intermediate with the molecular formula C21H30N2O5 and a molecular weight of 390.48. This compound is a critical building block in modern medicinal chemistry, valued for its complex molecular architecture that incorporates both morpholine and piperidine moieties. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents. The product, identified by CAS number 1146080-58-1, is supplied with a guaranteed purity to ensure consistency and reliability in demanding synthetic pathways.

Application

This specialized intermediate serves as a key precursor in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the research and development of new drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel pharmacophores.
• API Synthesis: Incorporated into multi-step synthetic routes for the production of complex active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule synthesis.

Basic Information

Item	Details
Product Name	3-[2-(Morpholine-4-Carbonyl)-Phenoxy]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1146080-58-1
Molecular Formula	C21H30N2O5
Molecular Weight	390.48 g/mol
Synonyms	tert-Butyl 3-[2-(morpholine-4-carbonyl)phenoxy]piperidine-1-carboxylate; 1-Boc-3-[2-(4-morpholinylcarbonyl)phenoxy]piperidine; 3-(2-Morpholin-4-yl-2-oxoethoxy)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-[2-(morpholine-4-carbonyl)phenoxy]piperidine; BOC-3-(2-Morpholinocarbonylphenoxy)piperidine; CAS 1146080-58-1
EINECS	Contact for details

Quality Control

Our 3-[2-(Morpholine-4-Carbonyl)-Phenoxy]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the specified 98+% purity and identity criteria. Standard quality control includes chromatographic purity analysis and spectroscopic identification. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.