Description

3-[4-(Morpholine-4-Carbonyl)-Phenoxy]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) chemical intermediate with a molecular weight of 390.48, identified by CAS number 1146080-06-9. This compound is a critical building block in modern pharmaceutical research and development, valued for its role in constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

This specialized intermediate is designed for advanced synthetic chemistry applications, particularly in drug discovery and development.

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Peptidomimetic Synthesis: Serves as a constrained scaffold in the design of peptide-like molecules with improved metabolic stability.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for API manufacturing.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	3-[4-(Morpholine-4-Carbonyl)-Phenoxy]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1146080-06-9
Molecular Formula	C21H30N2O5
Molecular Weight	390.48 g/mol
Synonyms	tert-Butyl 3-[4-(morpholine-4-carbonyl)phenoxy]piperidine-1-carboxylate; 1-Boc-3-(4-(morpholine-4-carbonyl)phenoxy)piperidine; 3-(4-(Morpholine-4-carbonyl)phenoxy)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-[4-(morpholin-4-ylcarbonyl)phenoxy]piperidine; BOC-3-(4-Morpholinocarbonylphenoxy)piperidine; 1146080-06-9; UNII-8K8V7X8Q6H
EINECS	Contact for details

Quality Control

Our 3-[4-(Morpholine-4-Carbonyl)-Phenoxy]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is analyzed to confirm identity and purity, with comprehensive testing that may include HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing all relevant specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.