Description

6-(3-Chlorophenyl)-2-Phenyl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Chemical Biology Research: Used as a core scaffold for designing and synthesizing chemical probes to study protein-ligand interactions and biological pathways.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization programs.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional laboratories for the development of new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-(3-Chlorophenyl)-2-Phenyl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One
CAS No.	1144494-44-9
Molecular Formula	C18H12ClN3O
Molecular Weight	321.76 g/mol
Synonyms	6-(3-Chlorophenyl)-2-phenyl-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-one; 3H-Pyrazolo[3,4-b]pyridin-3-one, 6-(3-chlorophenyl)-1,2-dihydro-2-phenyl-; 1144494-44-9; 6-(3-Chlorophenyl)-2-phenyl-3H-pyrazolo[3,4-b]pyridin-3-one; Pyrazolopyridine derivative CAS 1144494-44-9
EINECS	Contact for details

Quality Control

Our production of 6-(3-Chlorophenyl)-2-Phenyl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.