Description

6-(2-Chlorophenyl)-2-Phenyl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology, neurology, and anti-inflammatory applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic scaffolds due to its fused pyrazolopyridine core.
• Biochemical Research: Employed as a reference standard or a probe molecule in biochemical assays and pharmacological studies.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Applied in university and institutional labs for exploring new chemical reactions and developing novel synthetic methodologies.

Basic Information

Product Name	6-(2-Chlorophenyl)-2-Phenyl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One
CAS No.	1144490-29-8
Molecular Formula	C18H12ClN3O
Molecular Weight	321.76 g/mol
Synonyms	6-(2-Chlorophenyl)-2-phenyl-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-one; 3H-Pyrazolo[3,4-b]pyridin-3-one, 6-(2-chlorophenyl)-1,2-dihydro-2-phenyl-; 1144490-29-8; 2-Phenyl-6-(2-chlorophenyl)-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-one; Pyrazolopyridine derivative CAS 1144490-29-8
EINECS	Contact for details

Quality Control

Our production of 6-(2-Chlorophenyl)-2-Phenyl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.