Description

6-(5-Bromo-2-Thienyl)-2-Oxo-1,2-Dihydropyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining thiophene and pyridone rings. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Kinase Inhibitor Development: Employed in the synthesis of potential kinase inhibitors due to its privileged heterocyclic structure.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes to study biological pathways and target validation.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and new methodology development.

Basic Information

Product Name	6-(5-Bromo-2-Thienyl)-2-Oxo-1,2-Dihydropyridine-3-Carbonitrile
CAS No.	1144460-95-6
Molecular Formula	C10H5BrN2OS
Molecular Weight	281.13 g/mol
Synonyms	6-(5-Bromo-2-thienyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 3-Cyano-6-(5-bromo-2-thienyl)-2(1H)-pyridinone; 6-(5-Bromothiophen-2-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile; 2-Oxo-6-(5-bromo-2-thienyl)-1,2-dihydropyridine-3-carbonitrile; 1144460-95-6; 6-(5-Bromo-2-thienyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 6-(5-Bromo-2-Thienyl)-2-Oxo-1,2-Dihydropyridine-3-Carbonitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. All materials are characterized and verified using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.