Description

tert-Butyl 2-(1,4-Dioxaspiro[4.5]decan-8-yl)hydrazinecarboxylate is a specialized organic building block featuring a protected hydrazine moiety and a spirocyclic ketal group. This compound is valued for its role as a key synthetic intermediate in the development of complex molecules, particularly in pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing nitrogen heterocycles or hydrazine-derived functionalities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Acts as a reagent for bioconjugation or as a building block for activity-based probes and linkers.
• Material Science Research: Employed in the synthesis of specialty polymers, ligands for catalysis, or organic frameworks.
• Academic & Contract Research: A valuable tool for methodological development and exploratory organic synthesis in university and CRO laboratories.

Basic Information

Product Name	tert-Butyl 2-(1,4-Dioxaspiro[4.5]decan-8-yl)hydrazinecarboxylate
CAS No.	1144080-27-2
Molecular Formula	C15H26N2O4
Molecular Weight	298.38 g/mol
Synonyms	tert-Butyl (1,4-dioxaspiro[4.5]decan-8-yl)carbazate; 1,4-Dioxaspiro[4.5]decane-8-carboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]hydrazide; Boc-hydrazide of 1,4-dioxaspiro[4.5]decan-8-carboxylic acid; 8-[(tert-Butoxycarbonyl)hydrazinyl]-1,4-dioxaspiro[4.5]decane; tert-Butyl N'-(1,4-dioxaspiro[4.5]decan-8-yl)hydrazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(1,4-Dioxaspiro[4.5]decan-8-yl)hydrazinecarboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.