Description

5-tert-Butyl 3-Ethyl 1-Methyl-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridine-3,5-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for various therapeutic targets.
• CNS Drug Development: A crucial scaffold for synthesizing compounds targeting neurological and psychiatric disorders.
• Kinase Inhibitor Synthesis: Employed in the construction of molecules designed to modulate kinase activity for oncology and inflammatory diseases.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in universities and institutes for exploring novel heterocyclic chemistry and bioactivity.

Basic Information

Item	Detail
Product Name	5-tert-Butyl 3-Ethyl 1-Methyl-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridine-3,5-Dicarboxylate
CAS No.	1142210-81-8
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	1-Methyl-5-tert-butyl-3-ethyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-3,5-dicarboxylate; 5H-Pyrazolo[4,3-c]pyridine-3,5-dicarboxylic acid, 1,4,6,7-tetrahydro-5-(1,1-dimethylethyl)-3-ethyl 1-methyl ester; tert-Butyl 3-ethyl 1-methyl 1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-3,5-dicarboxylate; CAS 1142210-81-8
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl 3-Ethyl 1-Methyl-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridine-3,5-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP standards and supply chain traceability guarantees material integrity for your most sensitive R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.