Description

2-Bromo-5-(Piperidin-1-Yl)Pyridine is a versatile and high-value heterocyclic building block featuring a bromine substituent and a piperidine moiety. This compound is of significant interest for its role as a key intermediate in modern pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, ligands for catalysis, and advanced polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce the 5-(piperidin-1-yl)pyridine fragment.
• Chemical Biology & Medicinal Chemistry: Employed in the design and synthesis of molecular probes and compound libraries for high-throughput screening and target identification.

Basic Information

Product Name	2-Bromo-5-(Piperidin-1-Yl)Pyridine
CAS No.	1142197-44-1
Molecular Formula	C10H13BrN2
Molecular Weight	241.13 g/mol
Synonyms	2-Bromo-5-(1-piperidinyl)pyridine; 5-(Piperidin-1-yl)-2-bromopyridine; 2-Bromo-5-piperidin-1-ylpyridine; Pyridine, 2-bromo-5-(1-piperidinyl)-; 1142197-44-1; 2-Bromo-5-piperidinopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Piperidin-1-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.