Description

2-Bromo-5-Cyclobutylpyridine is a high-value brominated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring a cyclobutyl substituent, makes it an essential intermediate for constructing complex molecules with specific three-dimensional architectures. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Advanced Material Development: A building block for organic electronic materials and liquid crystals due to its rigid, conjugated structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Bromo-5-Cyclobutylpyridine
CAS No.	1142197-20-3
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	5-Cyclobutyl-2-bromopyridine; 2-Bromo-5-cyclobutyl-pyridine; Pyridine, 2-bromo-5-cyclobutyl-; 2-Bromopyridine-5-cyclobutyl; (5-Cyclobutylpyridin-2-yl)bromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Cyclobutylpyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and process development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to support regulatory filings and GMP (Good Manufacturing Practice) standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.