Description

2-Bromo-5-tert-Butyl-Pyridine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique steric and electronic properties, which enable precise molecular modifications in complex chemical architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the tert-butyl and bromo groups contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized pyridine cores.

Basic Information

Product Name	2-Bromo-5-tert-Butyl-Pyridine
CAS No.	1142197-19-0
Molecular Formula	C9H12BrN
Molecular Weight	214.10 g/mol
Synonyms	5-tert-Butyl-2-bromopyridine; 2-Bromo-5-(1,1-dimethylethyl)pyridine; 2-Bromo-5-(tert-butyl)pyridine; Pyridine, 2-bromo-5-(1,1-dimethylethyl)-; 2-Bromo-5-tert-butylpyridine; 5-(tert-Butyl)-2-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-tert-Butyl-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.