Description

4-Bromo-2-(Tetrahydrofuran-3-Yloxy)Pyridine is a high-value brominated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a bromine substituent and a tetrahydrofuran-3-yloxy ether linkage, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Building block for organic electronic materials, such as those used in OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Bromo-2-(Tetrahydrofuran-3-Yloxy)Pyridine
CAS No.	1142194-55-5
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	4-Bromo-2-[(oxolan-3-yl)oxy]pyridine; 2-(Tetrahydrofuran-3-yloxy)-4-bromopyridine; 4-Bromo-2-(tetrahydro-3-furanyloxy)pyridine; Pyridine, 4-bromo-2-[(tetrahydro-3-furanyl)oxy]-; 1142194-55-5; 4-Bromo-2-(THF-3-yloxy)pyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Tetrahydrofuran-3-Yloxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP (current Good Manufacturing Practice) environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.