Description

4-Bromo-2-cyclobutoxypyridine is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. Its core value lies in its functionalized pyridine and cyclobutyl ether structure, making it a critical synthon for constructing complex molecules in medicinal chemistry. This compound is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the pyridine moiety's bioactivity.
• Ligand & Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials and liquid crystals due to its aromatic and ether functionalities.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Institutional R&D: Used in university and research institute laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	4-Bromo-2-Cyclobutoxypyridine
CAS No.	1142194-51-1
Molecular Formula	C9H10BrNO
Molecular Weight	228.09 g/mol
Synonyms	2-Cyclobutoxy-4-bromopyridine; 4-Bromo-2-(cyclobutyloxy)pyridine; Pyridine, 4-bromo-2-cyclobutoxy-; 4-Bromo-2-cyclobutyloxypyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-cyclobutoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.