Description

4-Bromo-2-Pyrrolidin-1-Ylpyridine is a high-purity brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which facilitates the introduction of both bromo and pyrrolidinyl functional groups into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Material Development: Investigated as a monomer or intermediate in the synthesis of organic electronic materials and liquid crystals.

Basic Information

Product Name	4-Bromo-2-Pyrrolidin-1-Ylpyridine
CAS No.	1142194-47-5
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	4-Bromo-2-(1-pyrrolidinyl)pyridine; 2-Pyrrolidin-1-yl-4-bromopyridine; 4-Bromo-2-pyrrolidin-1-yl-pyridine; 4-Bromo-2-(pyrrolidin-1-yl)pyridine; 1-(4-Bromopyridin-2-yl)pyrrolidine; Pyrrolidine, 1-(4-bromo-2-pyridinyl)-; 1142194-47-5
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Pyrrolidin-1-Ylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.