Description

1-(4-Bromopyridin-2-Yl)Pyrrolidin-2-One is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant commercial interest. Its core value lies in its unique molecular structure, which is critical for synthesizing novel bioactive compounds, particularly in medicinal chemistry and drug discovery. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies for novel drug candidates.
• Agrochemical Synthesis: Serves as a precursor for developing new crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.
• Material Science Research: Investigated as a monomer or precursor for functional polymers and advanced organic materials.

Basic Information

Product Name	1-(4-Bromopyridin-2-Yl)Pyrrolidin-2-One
CAS No.	1142194-39-5
Molecular Formula	C9H9BrN2O
Molecular Weight	241.09 g/mol
Synonyms	1-(4-Bromo-2-pyridinyl)-2-pyrrolidinone; 2-Pyrrolidinone, 1-(4-bromo-2-pyridinyl)-; 4-Bromo-2-(2-oxopyrrolidin-1-yl)pyridine; 1-(4-Bromopyridin-2-yl)pyrrolidin-2-one; 1142194-39-5; 4-Bromo-2-(2-oxo-1-pyrrolidinyl)pyridine; 1-(4-Bromopyridin-2-yl)-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our 1-(4-Bromopyridin-2-Yl)Pyrrolidin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring suitability for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.