Description

4-Bromo-2-(2-Fluorophenyl)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Development: Used to create advanced herbicides, fungicides, and insecticides by introducing the fluorinated phenylpyridine scaffold.
• Material Science Research: Serves as a monomer or ligand precursor for developing organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create biaryl structures.
• Life Science Reagents: Used in the development of fluorescent probes, biomarkers, and other diagnostic tools.

Basic Information

Product Name	4-Bromo-2-(2-Fluorophenyl)Pyridine
CAS No.	1142194-21-5
Molecular Formula	C11H7BrFN
Molecular Weight	252.08 g/mol
Synonyms	2-(2-Fluorophenyl)-4-bromopyridine; 4-Bromo-2-(2-fluorophenyl)pyridine; 4-Bromo-2-(o-fluorophenyl)pyridine; 2-Fluoro-2'-(4-bromopyridinyl)benzene; Pyridine, 4-bromo-2-(2-fluorophenyl)-; 1142194-21-5; 4-Bromo-2-(2-fluorophenyl)pyridine (CAS 1142194-21-5)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(2-Fluorophenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request. We adhere to cGMP guidelines where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.