Description

4-Bromo-2-Cyclobutylpyridine is a high-value brominated pyridine derivative featuring a cyclobutyl substituent, serving as a critical building block in advanced organic synthesis. Its unique structure makes it an essential intermediate for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the bromine atom and pyridine core offer sites for further functionalization.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: A requested intermediate for custom synthesis projects and scale-up services under cGMP or ISO standards.

Basic Information

Product Name	4-Bromo-2-Cyclobutylpyridine
CAS No.	1142194-11-3
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	2-Cyclobutyl-4-bromopyridine; 4-Bromo-2-cyclobutylpyridine; Pyridine, 4-bromo-2-cyclobutyl-; 1142194-11-3; 4-Bromo-2-cyclobutyl-pyridine; 4-Brom-2-cyclobutylpyridin; 4-Bromo-2-(cyclobutyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Cyclobutylpyridine is produced and analyzed under strict quality management systems. We provide comprehensive analytical documentation, including HPLC, GC, NMR, and mass spectrometry data, to verify identity, purity, and consistency. Certificates of Analysis (COA) are available for all shipments, and we support compliance with relevant regulatory frameworks for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Residue on Ignition	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.