Description

1-(7-Bromo-4-Methyl-3,4-Dihydropyrido[2,3-B]-Pyrazin-1(2H)-Yl)-2,2-Dimethylpropan-1-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a critical building block for medicinal chemistry research and development, enabling the creation of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and API manufacturers focused on developing innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used by R&D scientists for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial building block in the multi-step synthesis of complex target molecules for clinical evaluation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of investigational new drugs.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1-(7-Bromo-4-Methyl-3,4-Dihydropyrido[2,3-B]-Pyrazin-1(2H)-Yl)-2,2-Dimethylpropan-1-One
CAS No.	1142192-65-1
Molecular Formula	C14H18BrN3O
Molecular Weight	324.22 g/mol
Synonyms	1-(7-Bromo-4-methyl-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-1-yl)-2,2-dimethylpropan-1-one; 2,2-Dimethyl-1-(4-methyl-7-bromo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-1-yl)propan-1-one; 7-Bromo-4-methyl-1-(2,2-dimethylpropanoyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine; 1142192-65-1; Pivaloyl derivative of 7-bromo-4-methyl-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine
EINECS	Contact for details

Quality Control

Our 1-(7-Bromo-4-Methyl-3,4-Dihydropyrido[2,3-B]-Pyrazin-1(2H)-Yl)-2,2-Dimethylpropan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.