Description

n-(2-(Trimethylsilyl)Furo[3,2-B]Pyridin-7-Yl)-Pivalamide is a high-purity, advanced pharmaceutical intermediate featuring a unique fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers seeking reliable, high-quality building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its complex fused-ring scaffold.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, leveraging the reactivity of the furopyridine and trimethylsilyl-protected groups.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for developing new synthetic methodologies and exploring novel heterocyclic chemistry.

Basic Information

Product Name	n-(2-(Trimethylsilyl)Furo[3,2-B]Pyridin-7-Yl)-Pivalamide
CAS No.	1142192-62-8
Molecular Formula	C17H24N2O2Si
Molecular Weight	316.48 g/mol
Synonyms	Pivalamide, N-[2-(trimethylsilyl)furo[3,2-b]pyridin-7-yl]-; 2,2-Dimethyl-N-[2-(trimethylsilyl)furo[3,2-b]pyridin-7-yl]propanamide; 7-Pivalamido-2-trimethylsilylfuro[3,2-b]pyridine; N-(2-(Trimethylsilyl)furo[3,2-b]pyridin-7-yl)-2,2-dimethylpropanamide; 1142192-62-8; Furo[3,2-b]pyridine-7-carboxamide, N-[2-(trimethylsilyl)]-, 2,2-dimethyl-
EINECS	Contact for details

Quality Control

Our n-(2-(Trimethylsilyl)Furo[3,2-B]Pyridin-7-Yl)-Pivalamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.