Description

tert-Butyl 6-Bromo-5-Pivalamidopyridin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is essential for research and development in medicinal chemistry, particularly in the construction of complex heterocyclic molecules. It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API manufacturing processes under GMP conditions.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and client-specific molecule development.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 6-Bromo-5-Pivalamidopyridin-3-Ylcarbamate
CAS No.	1142192-53-7
Molecular Formula	C15H22BrN3O3
Molecular Weight	372.26 g/mol
Synonyms	tert-Butyl (6-bromo-5-(pivalamido)pyridin-3-yl)carbamate; 6-Bromo-5-(2,2-dimethylpropanamido)pyridin-3-yl tert-butyl carbamate; 5-(tert-Butoxycarbonylamino)-3-bromo-2-pivalamidopyridine; tert-Butyl N-[6-bromo-5-(2,2-dimethylpropanoylamino)-3-pyridyl]carbamate; BOC-6-Bromo-5-Pivalamidopyridin-3-Ylamine; 1142192-53-7
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 6-Bromo-5-Pivalamidopyridin-3-Ylcarbamate adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive pharmaceutical applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects with specifications that can meet the requirements of cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.